HitPredict

Interactor 1: MDHC (P14152)
Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Aromatic alpha-keto acid reductase) (KAR) (EC 1.1.1.96) (Cytosolic malate dehydrogenase)
Gene: Mdh1

Interactor 2: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31040226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 334 Mm			1 1115
+	Mm
		535744 MDHC_MOUSE (1-334): 9.91e-142: 405: 100.00		HDAC5_MOUSE (1-1115): 0: 788: 99.28
+	Mm
		410700 LDHA_MOUSE (2-330): 5.64e-123: 358: 20.42		Q3UJF1_MOUSE (1-1115): 0: 796: 100.00
+	Mm
		410722 LDHA_MOUSE (2-330): 5.64e-123: 358: 20.42		HDAC5_MOUSE (1-1115): 0: 788: 99.28
+	Hs
		334311 LDHA_HUMAN (3-330): 2.18e-123: 359: 20.18		HDAC5_HUMAN (1-1115): 0: 760: 94.49
+	Mm
		439206 MDHM_MOUSE (6-331): 5.51e-57: 189: 20.59		Q3UJF1_MOUSE (1-1115): 0: 796: 100.00
+	Mm
		439216 MDHM_MOUSE (6-331): 5.51e-57: 189: 20.59		HDAC5_MOUSE (1-1115): 0: 788: 99.28
+	Hs
		777789 MDHM_HUMAN (6-333): 2.44e-56: 188: 20.18		HDAC5_HUMAN (1-1115): 0: 760: 94.49
+	Hs
		777516 MDHM_HUMAN (6-333): 2.44e-56: 188: 20.18		HDAC4_HUMAN (3-1095): 0: 697: 55.51
+	Hs
		334196 LDHA_HUMAN (3-330): 2.18e-123: 359: 20.18		HDAC1_HUMAN (666-1072): 2.18e-153: 467: 21.70
+	Hs
		334300 LDHA_HUMAN (3-330): 2.18e-123: 359: 20.18		HDAC6_HUMAN (611-1061): 9.97e-109: 370: 31.77
+	Hs
		422112 LDHB_HUMAN (6-329): 2.36e-118: 346: 21.34		HDAC6_HUMAN (611-1061): 9.97e-109: 370: 31.77