Interactor 1: IRF2 (P14316)
Interferon regulatory factor 2 (IRF-2)
Gene: IRF2

Interactor 2: SPI1 (P17947)
Transcription factor PU.1 (31 kDa-transforming protein)
Gene: SPI1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 17200120
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 5 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 349
Hs

1 270
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024