HitPredict

Interactor 1: HCLS1 (P14317)
Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75)
Gene: HCLS1

Interactor 2: SNX1 (Q13596)
Sorting nexin-1
Gene: SNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 522
+	Hs
		536593 HCLS1_HUMAN (1-486): 9.61e-143: 420: 100.00		SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45
+	Hs
		536591 HCLS1_HUMAN (1-486): 9.61e-143: 420: 100.00		SNX6_HUMAN (145-520): 1.81e-73: 240: 20.46
+	Hs
		1040498 STAM1_HUMAN (358-482): 2e-13: 74.5: 21.60		SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00
+	Hs
		1356882 ASAP1_HUMAN (206-485): 2.99e-35: 142: 18.25		SNX9_HUMAN (2-518): 1.33e-93: 298: 14.58
+	Hs
		581079 PLCG1_HUMAN (55-485): 1.1e-40: 158: 17.41		SNX7_HUMAN (114-515): 3.23e-86: 273: 19.65
+	Hs
		1300855 ABI2_HUMAN (269-485): 3.95e-14: 76.5: 22.22		SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15
+	Hs
		1348430 ABI2_HUMAN (269-485): 3.95e-14: 76.5: 22.22		SNX7_HUMAN (114-515): 3.23e-86: 273: 19.65
+	Hs
		1078937 ITSN1_HUMAN (339-485): 3.14e-11: 68.1: 20.25		SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45
+	Hs
		1078933 ITSN1_HUMAN (339-485): 3.14e-11: 68.1: 20.25		SNX6_HUMAN (145-520): 1.81e-73: 240: 20.46
+	Hs
		1316002 PACN1_HUMAN (138-485): 3.98e-34: 135: 15.01		SNX12_HUMAN (106-272): 2.12e-46: 161: 27.55
+	Hs
		581087 PLCG1_HUMAN (55-485): 1.1e-40: 158: 17.41		SNX11_HUMAN (137-268): 7.22e-31: 122: 31.34