HitPredict

Interactor 1: FPPS (P14324)
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)
Gene: FDPS

Interactor 2: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.620

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 419 Hs			1 815
+	Mm
		869158 FPPS_MOUSE (67-419): 3.48e-148: 426: 84.42		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Hs
		320604 GGPPS_HUMAN (111-418): 2.43e-61: 202: 20.70		ATX1_HUMAN (1-815): 0: 1349: 100.00