HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.964

The method score is based on:

Property Details
Experiments 25416956, 27107012, 11331580, 19351825, 17156811, 9247190, 22829933
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid array, barcode fusion genetics two hybrid, split luciferase complementation, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~PRY, PRY~SPRY, SPRY~SPRY, zf-B_box~zf-B_box, zf-C3HC4_4~zf-C3HC4_4
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001650 - fibrillar center
GO:0002820 - negative regulation of adaptive immune response
GO:0003676 - nucleic acid binding
GO:0003677 - DNA binding
and 34 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024