HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	25416956, 32707033
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 499
+	Hs
		584875 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		833915 TRI50_HUMAN (1-488): 4.24e-121: 365: 27.53		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		584957 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Mm
		509482 TRI72_MOUSE (1-497): 3.65e-108: 332: 25.84		CDK1_MOUSE (160-485): 2.85e-113: 338: 24.25