HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Hs			1 193
+	Hs
		536996 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E2_HUMAN (4-193): 2.5e-84: 249: 81.96
+	Hs
		537142 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D4_HUMAN (47-192): 2.38e-81: 239: 63.01
+	Hs
		536779 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		536760 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		536965 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E3_HUMAN (3-193): 1.26e-78: 235: 77.49
+	Hs
		536772 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		536774 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95
+	Hs
		536757 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2A_HUMAN (44-190): 1.1e-70: 212: 36.74
+	Hs
		1297370 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E2_HUMAN (4-193): 2.5e-84: 249: 81.96
+	Hs
		584910 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2E1_HUMAN (19-193): 2.75e-82: 244: 100.00
+	Hs
		851889 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E1_HUMAN (19-193): 2.75e-82: 244: 100.00
+	Hs
		584923 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		584907 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		919870 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		584916 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		849453 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		1282350 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E3_HUMAN (3-193): 1.26e-78: 235: 77.49
+	Hs
		895921 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		584918 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95
+	Hs
		896547 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95