HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	38113892, 19549727
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Hs			1 183
+	Hs
		537142 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08
+	Hs
		536779 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		536760 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		536772 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		536965 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00
+	Hs
		536996 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33
+	Hs
		536757 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46
+	Hs
		536763 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Hs
		584923 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		584907 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		1336390 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08
+	Hs
		919870 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		584916 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		849453 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		895921 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		1282350 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00
+	Hs
		1297370 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33
+	Hs
		584910 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Hs
		584920 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		851889 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33