HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Hs			1 207
+	Hs
		536996 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02
+	Hs
		537142 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01
+	Hs
		536779 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Hs
		536760 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D1_HUMAN (61-206): 9.93e-82: 241: 61.64
+	Hs
		536772 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		536763 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E1_HUMAN (35-207): 2.62e-79: 236: 87.36
+	Hs
		536757 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2A_HUMAN (59-204): 1.17e-69: 210: 35.62
+	Hs
		536774 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27
+	Hs
		1282350 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00
+	Hs
		1297370 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02
+	Hs
		584923 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Hs
		584907 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D1_HUMAN (61-206): 9.93e-82: 241: 61.64
+	Hs
		919870 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Hs
		584916 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		849453 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D1_HUMAN (61-206): 9.93e-82: 241: 61.64
+	Hs
		584910 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2E1_HUMAN (35-207): 2.62e-79: 236: 87.36
+	Hs
		895921 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		851889 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E1_HUMAN (35-207): 2.62e-79: 236: 87.36
+	Hs
		584918 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27
+	Hs
		896547 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27