HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 548
+	Hs
		536726 TRI27_HUMAN (1-513): 0: 523: 100.00		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		536970 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI43_HUMAN (13-395): 3.07e-73: 242: 13.06
+	Hs
		537045 TRI27_HUMAN (1-513): 0: 523: 100.00		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		537123 TRI27_HUMAN (1-513): 0: 523: 100.00		TRIM1_HUMAN (17-367): 3.2e-63: 222: 21.28
+	Hs
		536717 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		537046 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI31_HUMAN (12-426): 1.42e-62: 213: 17.35
+	Hs
		536980 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI11_HUMAN (12-402): 5.69e-62: 212: 16.88
+	Hs
		175635 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI18_HUMAN (46-330): 5.85e-60: 211: 23.43
+	Hs
		262150 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		585075 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI39_HUMAN (17-414): 4.23e-77: 254: 15.74
+	Hs
		1336382 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRI39_HUMAN (17-414): 4.23e-77: 254: 15.74
+	Hs
		584870 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		585058 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM5_HUMAN (13-396): 3.08e-68: 230: 14.32
+	Hs
		585056 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		1318352 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		585057 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI31_HUMAN (12-426): 1.42e-62: 213: 17.35
+	Hs
		537047 TRI27_HUMAN (1-513): 0: 523: 100.00		TRIM9_HUMAN (124-288): 9.61e-12: 69.7: 26.06
+	Hs
		584993 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39