HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: TRIM9 (Q9C026)
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9)
Gene: TRIM9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PRY~SPRY, SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-C3HC4
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 710
+	Hs
		175635 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI18_HUMAN (1-709): 4.89e-141: 430: 24.02
+	Hs
		584993 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI67_HUMAN (4-700): 4.16e-154: 467: 60.98
+	Hs
		537123 TRI27_HUMAN (1-513): 0: 523: 100.00		TRIM1_HUMAN (1-708): 7.26e-132: 408: 22.48
+	Hs
		536745 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI23_HUMAN (119-420): 6.71e-63: 221: 20.88
+	Hs
		301588 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI37_HUMAN (156-519): 2.44e-43: 170: 20.56
+	Hs
		301609 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI37_HUMAN (156-519): 2.44e-43: 170: 20.56
+	Hs
		536726 TRI27_HUMAN (1-513): 0: 523: 100.00		RO52_HUMAN (1-164): 3.45e-24: 108: 15.24
+	Hs
		536980 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI11_HUMAN (3-147): 2.98e-20: 96.3: 17.93
+	Hs
		536717 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI27_HUMAN (2-163): 2.41e-16: 84.7: 19.75
+	Hs
		585075 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI39_HUMAN (1-521): 8.01e-30: 126: 12.21
+	Hs
		1336382 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRI39_HUMAN (1-521): 8.01e-30: 126: 12.21
+	Hs
		537043 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI55_HUMAN (1-56): 1.37e-09: 63.3: 35.09
+	Hs
		262150 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM3_HUMAN (1-709): 7.49e-28: 121: 11.53
+	Hs
		585058 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM5_HUMAN (3-164): 1.38e-25: 113: 14.37
+	Hs
		584870 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		RO52_HUMAN (1-164): 3.45e-24: 108: 15.24
+	Hs
		1290865 TRI11_HUMAN (1-500): 9.03e-148: 433: 38.00		TRI11_HUMAN (3-147): 2.98e-20: 96.3: 17.93
+	Hs
		1245269 TRI58_HUMAN (1-493): 2.59e-145: 427: 34.00		TRI58_HUMAN (2-167): 2.07e-14: 78.2: 14.62