Interactor 1: DRD2 (P14416)
D(2) dopamine receptor (Dopamine D2 receptor)
Gene: DRD2

Interactor 2: OPRM (P35372)
Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)
Gene: OPRM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 31416253
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0001965 - G-protein alpha-subunit binding
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0007200 - phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0008285 - negative regulation of cell population proliferation
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 443
Hs

1 400
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024