HitPredict

Interactor 1: DRD2 (P14416)
D(2) dopamine receptor (Dopamine D2 receptor)
Gene: DRD2

Interactor 2: KCNJ3 (P48549)
G protein-activated inward rectifier potassium channel 1 (GIRK-1) (Inward rectifier K(+) channel Kir3.1) (Potassium channel, inwardly rectifying subfamily J member 3)
Gene: KCNJ3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12297500
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0042734 - presynaptic membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 501
+	Hs
		602190 DRD4_HUMAN (42-443): 2.01e-63: 212: 35.70		KCNJ3_HUMAN (1-501): 0: 848: 100.00
+	Hs
		428968 ADRB2_HUMAN (322-442): 1.41e-27: 115: 35.54		KCNJ3_HUMAN (1-501): 0: 848: 100.00
+	Hs
		537266 DRD2_HUMAN (1-443): 9.85e-112: 337: 100.00		KCNJ6_HUMAN (40-383): 0: 571: 61.63
+	Hs
		537267 DRD2_HUMAN (1-443): 9.85e-112: 337: 100.00		KCNJ5_HUMAN (9-375): 0: 563: 58.61
+	Hs
		602189 DRD4_HUMAN (42-443): 2.01e-63: 212: 35.70		KCNJ5_HUMAN (9-375): 0: 563: 58.61
+	Hs
		602205 DRD4_HUMAN (42-443): 2.01e-63: 212: 35.70		KCNJ9_HUMAN (33-383): 0: 544: 59.94
+	Hs
		428966 ADRB2_HUMAN (322-442): 1.41e-27: 115: 35.54		KCNJ6_HUMAN (40-383): 0: 571: 61.63
+	Hs
		428967 ADRB2_HUMAN (322-442): 1.41e-27: 115: 35.54		KCNJ5_HUMAN (9-375): 0: 563: 58.61