HitPredict

Interactor 1: HA2B (P14434)
H-2 class II histocompatibility antigen, A-B alpha chain (IAalpha)
Gene: H2-Aa

Interactor 2: HB2A (P14483)
H-2 class II histocompatibility antigen, A beta chain
Gene: H2-Ab1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 12084926, 12589760
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_II_beta, C1-set~MHC_II_alpha, MHC_II_alpha~MHC_II_beta
Common GO terms GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0019882 - antigen processing and presentation
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 256
Mm

1 265
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024