HitPredict

Interactor 1: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	8766817, 22745667
Identification Methods	pull down, unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0017124 - SH3 domain binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 443
+	Mm
		1141333 NCK1_MOUSE (130-350): 2.3e-33: 129: 17.16		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		557667 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991863 SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		209037 NCK2_HUMAN (161-327): 3.03e-19: 90.2: 14.98		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991902 ITSN2_HUMAN (8-390): 2.54e-15: 80.2: 11.00		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991805 DNMBP_HUMAN (161-281): 1.1e-12: 71.7: 19.23		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991778 ITSN1_HUMAN (54-227): 2.01e-11: 67.7: 12.16		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991791 SPD2A_HUMAN (206-381): 1.55e-10: 65.1: 20.00		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991842 SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Dm
		1360803 Q9VA36_DROME (163-311): 4.93e-18: 87.9: 20.59		Q9W255_DROME (59-398): 6.04e-96: 295: 32.35
+	Hs
		1052207 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		209060 NCK2_HUMAN (161-327): 3.03e-19: 90.2: 14.98		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33