HitPredict

Interactor 1: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Interactor 2: WASF1 (Q92558)
Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12855698
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Hs			1 559
+	Mm
		1206482 VINEX_MOUSE (132-382): 3.33e-37: 145: 17.76		WASF2_MOUSE (1-374): 2.98e-111: 342: 46.19
+	Hs
		557755 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		WASF1_HUMAN (1-559): 2.63e-73: 245: 100.00
+	Hs
		298991 SRBS2_HUMAN (163-283): 1.9e-20: 95.7: 21.15		WASF1_HUMAN (1-559): 2.63e-73: 245: 100.00
+	Hs
		209133 NCK2_HUMAN (161-327): 3.03e-19: 90.2: 14.98		WASF1_HUMAN (1-559): 2.63e-73: 245: 100.00
+	Rn
		192742 SRBS2_RAT (163-283): 2.18e-21: 98.4: 21.15		Q5FWU0_RAT (1-291): 5.25e-59: 206: 52.58
+	Hs
		1052366 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		557843 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		166030 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		SYNJ2_HUMAN (46-507): 2.06e-31: 132: 13.92
+	Hs
		203224 MYO1E_HUMAN (3-283): 4.56e-53: 191: 15.20		SYNJ1_HUMAN (41-523): 2.02e-11: 69: 12.53
+	Hs
		998698 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		1052365 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		CABIN_HUMAN (242-556): 5.56e-27: 118: 17.45
+	Hs
		557670 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		ACK1_HUMAN (148-530): 2.56e-25: 112: 19.49
+	Hs
		992576 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		ACK1_HUMAN (148-530): 2.56e-25: 112: 19.49
+	Rn
		192744 SRBS2_RAT (163-283): 2.18e-21: 98.4: 21.15		SYNJ1_RAT (123-554): 5.15e-35: 142: 12.99
+	Mm
		101448 SH3G1_MOUSE (6-218): 8.41e-32: 125: 11.95		F8VPR5_MOUSE (80-528): 6.2e-24: 109: 12.17
+	Mm
		222878 NCK1_MOUSE (130-350): 2.3e-33: 129: 17.16		ACK1_MOUSE (162-530): 2.06e-21: 100: 18.09
+	Hs
		209039 NCK2_HUMAN (161-327): 3.03e-19: 90.2: 14.98		ACK1_HUMAN (148-530): 2.56e-25: 112: 19.49
+	Hs
		203208 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		SYNJ1_HUMAN (41-523): 2.02e-11: 69: 12.53
+	Hs
		203249 SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68		SYNJ1_HUMAN (41-523): 2.02e-11: 69: 12.53
+	Hs
		203192 SRBS2_HUMAN (163-283): 1.9e-20: 95.7: 21.15		SYNJ1_HUMAN (41-523): 2.02e-11: 69: 12.53