HitPredict

Interactor 1: INSRR (P14616)
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
Gene: INSRR

Interactor 2: AL3A2 (P51648)
Aldehyde dehydrogenase family 3 member A2 (EC 1.2.1.3) (EC 1.2.1.94) (Aldehyde dehydrogenase 10) (Fatty aldehyde dehydrogenase) (Microsomal aldehyde dehydrogenase)
Gene: ALDH3A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1297 Hs			1 485
+	Hs
		435589 IGF1R_HUMAN (9-1265): 0: 1222: 55.39		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		411340 INSR_HUMAN (27-1288): 0: 1183: 52.18		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		848814 EPHA5_HUMAN (454-1279): 0: 591: 19.78		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		665457 EPHA8_HUMAN (454-1268): 2.42e-179: 558: 20.16		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		848999 ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		384344 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		AL1B1_HUMAN (1-434): 0: 534: 24.55
+	Hs
		169168 MUSK_HUMAN (973-1242): 8.31e-67: 245: 42.61		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		384085 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		ALDH2_HUMAN (1-434): 0: 526: 23.44
+	Hs
		384519 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		848856 NTRK3_HUMAN (957-1242): 2.05e-62: 231: 40.84		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		507918 FGFR1_HUMAN (948-1294): 6.81e-59: 221: 35.90		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		601857 ERBB3_HUMAN (2-296): 3.16e-34: 145: 18.24		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		445834 ROS1_HUMAN (764-900): 8.58e-11: 68.9: 22.63		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Rn
		102594 INSR_RAT (5-179): 3.17e-10: 67: 19.78		G3V9W6_RAT (1-464): 1.97e-170: 493: 85.99