Interactor 1: KPYM (P14618)
Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58)
Gene: PKM

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 21988832
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0042803 - protein homodimerization activity
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 531
Hs

1 551
+ Hs

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Last updated: 15 Jul 2024