HitPredict

Interactor 1: A1Z921 (A1Z921)
Frazzled, isoform B
Gene: fra

Interactor 2: TRIM9 (M9MRI4)
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (Anomalies in sensory axon patterning protein) (asap) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif containing protein 9)
Gene: TRIM9

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22084112
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	fn3~fn3, I-set~fn3, Ig_3~fn3
Common GO terms	GO:0007411 - axon guidance GO:0016199 - axon midline choice point recognition GO:0044295 - axonal growth cone
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1375 Dm			1 740
+	Hs
		489979 PTPRF_HUMAN (3-1100): 1.01e-102: 364: 18.15		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Hs
		1172496 ROBO1_HUMAN (246-1121): 2.14e-81: 297: 18.69		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Hs
		1171073 NRCAM_HUMAN (341-1328): 4.28e-68: 254: 11.93		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Hs
		1018298 CNTN1_HUMAN (361-1332): 1.97e-64: 240: 12.89		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Hs
		685317 L1CAM_HUMAN (339-1361): 4.17e-61: 232: 11.45		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Hs
		793657 DCC_HUMAN (3-752): 2.83e-45: 181: 13.33		TRIM9_HUMAN (1-737): 5.48e-164: 491: 40.51
+	Hs
		1171077 NEO1_HUMAN (4-759): 4.36e-47: 187: 13.93		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Mm
		936318 DCC_MOUSE (3-752): 3.53e-45: 181: 13.46		TRI67_MOUSE (1-735): 1.03e-149: 456: 38.16
+	Hs
		793643 DCC_HUMAN (3-752): 2.83e-45: 181: 13.33		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Hs
		1171804 ROBO2_HUMAN (41-430): 3.01e-24: 113: 27.70		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Ce
		107383 UNC40_CAEEL (530-1351): 9.2e-34: 144: 9.20		Q9UAQ3_CAEEL (1-735): 3.25e-124: 390: 38.37
+	Hs
		1171020 TITIN_HUMAN (5-157): 8.79e-10: 66: 17.06		TRI67_HUMAN (1-735): 8.49e-148: 452: 38.40
+	Hs
		1264797 TITIN_HUMAN (5-157): 8.79e-10: 66: 17.06		TRI55_HUMAN (129-460): 7.1e-89: 291: 18.92
+	Hs
		1264780 TITIN_HUMAN (5-157): 8.79e-10: 66: 17.06		TRI63_HUMAN (129-459): 1.12e-88: 284: 20.78
+	Hs
		1264796 TITIN_HUMAN (5-157): 8.79e-10: 66: 17.06		TRI54_HUMAN (129-460): 3.95e-87: 280: 19.82