HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36880596
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001666 - response to hypoxia GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 803 Hs			1 882
+	Hs
		437920 HS90B_HUMAN (75-783): 0: 997: 46.54		PML_HUMAN (1-882): 0: 902: 100.00
+	Hs
		170238 ENPL_HUMAN (1-803): 0: 1073: 100.00		TIF1A_HUMAN (27-546): 1.94e-62: 231: 16.49
+	Hs
		538271 ENPL_HUMAN (1-803): 0: 1073: 100.00		TRI68_HUMAN (43-408): 1.41e-53: 195: 12.37
+	Hs
		62676 ENPL_HUMAN (1-803): 0: 1073: 100.00		TRI64_HUMAN (48-415): 7.27e-54: 195: 14.32
+	Hs
		438499 HS90B_HUMAN (75-783): 0: 997: 46.54		TRIM8_HUMAN (51-553): 2.61e-68: 239: 14.68
+	Hs
		438503 HS90B_HUMAN (75-783): 0: 997: 46.54		TRIM2_HUMAN (37-579): 1.33e-55: 207: 13.28
+	Hs
		437880 HS90B_HUMAN (75-783): 0: 997: 46.54		RO52_HUMAN (44-414): 8.03e-56: 202: 13.46
+	Hs
		175632 HS90A_HUMAN (60-783): 0: 990: 45.34		TRI18_HUMAN (48-411): 5.87e-56: 207: 14.22
+	Hs
		432239 HS90A_HUMAN (60-783): 0: 990: 45.34		TRIM2_HUMAN (37-579): 1.33e-55: 207: 13.28
+	Hs
		438479 HS90B_HUMAN (75-783): 0: 997: 46.54		TRI56_HUMAN (34-536): 3.5e-53: 200: 18.41
+	Hs
		432214 HS90A_HUMAN (60-783): 0: 990: 45.34		TRI56_HUMAN (34-536): 3.5e-53: 200: 18.41
+	Hs
		438502 HS90B_HUMAN (75-783): 0: 997: 46.54		TRIM6_HUMAN (45-465): 1.09e-51: 190: 12.03
+	Hs
		437829 HS90B_HUMAN (75-783): 0: 997: 46.54		TRI49_HUMAN (45-406): 2.63e-50: 185: 12.43
+	Hs
		431456 HS90A_HUMAN (60-783): 0: 990: 45.34		TRI49_HUMAN (45-406): 2.63e-50: 185: 12.43
+	Hs
		438549 HS90B_HUMAN (75-783): 0: 997: 46.54		TRI36_HUMAN (55-384): 5.81e-17: 87.9: 18.51
+	Hs
		432284 HS90A_HUMAN (60-783): 0: 990: 45.34		TRI36_HUMAN (55-384): 5.81e-17: 87.9: 18.51