HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: BLK (P51451)
Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)
Gene: BLK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 803 Hs			1 505
+	Hs
		411978 ENPL_HUMAN (1-803): 0: 1073: 100.00		FYN_HUMAN (1-503): 0: 562: 54.75
+	Hs
		433552 ENPL_HUMAN (1-803): 0: 1073: 100.00		LYN_HUMAN (1-505): 0: 551: 59.77
+	Hs
		438007 HS90B_HUMAN (75-783): 0: 997: 46.54		BLK_HUMAN (1-505): 0: 600: 100.00
+	Hs
		437817 HS90B_HUMAN (75-783): 0: 997: 46.54		HCK_HUMAN (1-505): 0: 574: 62.92
+	Hs
		411556 HS90B_HUMAN (75-783): 0: 997: 46.54		LCK_HUMAN (1-505): 0: 569: 59.15
+	Hs
		411551 HS90A_HUMAN (60-783): 0: 990: 45.34		LCK_HUMAN (1-505): 0: 569: 59.15
+	Hs
		411949 HS90B_HUMAN (75-783): 0: 997: 46.54		FYN_HUMAN (1-503): 0: 562: 54.75
+	Hs
		437847 HS90B_HUMAN (75-783): 0: 997: 46.54		SRC_HUMAN (1-503): 0: 560: 54.22
+	Hs
		433218 HS90B_HUMAN (75-783): 0: 997: 46.54		YES_HUMAN (1-503): 0: 555: 53.15
+	Hs
		433526 HS90B_HUMAN (75-783): 0: 997: 46.54		LYN_HUMAN (1-505): 0: 551: 59.77
+	Hs
		437823 HS90B_HUMAN (75-783): 0: 997: 46.54		FGR_HUMAN (1-503): 0: 550: 53.61
+	Hs
		437967 HS90B_HUMAN (75-783): 0: 997: 46.54		FRK_HUMAN (32-502): 1.83e-179: 515: 45.94
+	Hs
		437966 HS90B_HUMAN (75-783): 0: 997: 46.54		ABL2_HUMAN (8-503): 2.23e-165: 500: 38.67
+	Hs
		337314 HS90B_HUMAN (75-783): 0: 997: 46.54		ABL1_HUMAN (54-504): 6.77e-163: 492: 41.09
+	Hs
		337312 HS90A_HUMAN (60-783): 0: 990: 45.34		ABL1_HUMAN (54-504): 6.77e-163: 492: 41.09
+	Hs
		438107 HS90B_HUMAN (75-783): 0: 997: 46.54		ITK_HUMAN (29-496): 7.21e-159: 466: 36.18
+	Hs
		438525 HS90B_HUMAN (75-783): 0: 997: 46.54		SRMS_HUMAN (19-498): 7.53e-160: 464: 39.59
+	Hs
		438098 HS90B_HUMAN (75-783): 0: 997: 46.54		BTK_HUMAN (4-498): 2.89e-156: 461: 34.12
+	Hs
		438160 HS90B_HUMAN (75-783): 0: 997: 46.54		PTK6_HUMAN (60-493): 7.36e-158: 458: 40.68
+	Hs
		437960 HS90B_HUMAN (75-783): 0: 997: 46.54		CSK_HUMAN (51-495): 1.16e-155: 452: 36.54