HitPredict

Interactor 1: CCNB1 (P14635)
G2/mitotic-specific cyclin-B1
Gene: CCNB1

Interactor 2: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.738

Property	Details
Experiments	32076268, 25750436, 35440621, 16479161, 12097298, 20733055, 16921029
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol and 1 others more... GO:0051301 - cell division
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 433 Hs			1 824
+	Hs
		590130 CCNA2_HUMAN (9-421): 3.65e-112: 338: 29.12		CDC27_HUMAN (1-824): 0: 625: 100.00
+	Rn
		1118804 Q6GX89_RAT (140-421): 2.12e-98: 297: 32.98		CDC27_RAT (1-824): 0: 600: 97.33
+	Hs
		174599 CCNB1_HUMAN (1-433): 6.07e-159: 457: 100.00		OGT1_HUMAN (77-583): 5.18e-24: 110: 9.25
+	Hs
		538535 CCNB1_HUMAN (1-433): 6.07e-159: 457: 100.00		CDC16_HUMAN (391-803): 1.46e-13: 76.5: 10.20
+	At
		1104385 CCA23_ARATH (7-423): 4.19e-115: 346: 28.11		CDC23_ARATH (343-819): 2.23e-28: 123: 11.02
+	At
		672515 CCB11_ARATH (14-422): 9.3e-107: 324: 27.53		CD27A_ARATH (540-823): 9.92e-32: 134: 17.61
+	Dm
		593439 CCNB_DROME (5-426): 3.55e-97: 302: 34.09		Q9I7L8_DROME (452-822): 1.1e-28: 124: 15.22
+	Sc
		561110 CG22_YEAST (5-416): 1.45e-101: 312: 30.36		CDC23_YEAST (367-810): 4.46e-23: 106: 12.39