HitPredict

Interactor 1: UBC3 (P14682)
Ubiquitin-conjugating enzyme E2-34 kDa (EC 2.3.2.23) (Cell division control protein 34) (E2 ubiquitin-conjugating enzyme 3) (E3 ubiquitin ligase complex SCF subunit CDC34) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: CDC34

Interactor 2: UBA1 (P22515)
Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45)
Gene: UBA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.952

The method score is based on:

Property Details
Experiments 17114057, 22949505, 7862115, 12861024, 31341161, 33888705
Identification Methods enzymatic study, affinity chromatography technology, x-ray crystallography, pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 295
Sc

1 1024
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024