HitPredict

Interactor 1: PP2B2 (P14747)
Serine/threonine-protein phosphatase 2B catalytic subunit A2 (EC 3.1.3.16) (Calcineurin A2) (Calmodulin-binding protein 2)
Gene: CMP2

Interactor 2: CANB (P25296)
Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit)
Gene: CNB1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.942

The method score is based on:

Property Details
Experiments 11805837, 16554755, 37968396, 20489023, 16429126, 18467557
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification, dihydrofolate reductase reconstruction
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Metallophos
Common GO terms GO:0005955 - calcineurin complex
GO:0006873 - intracellular monoatomic ion homeostasis
GO:0022604 - regulation of cell morphogenesis
GO:0031505 - fungal-type cell wall organization
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 604
Sc

1 175
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024