HitPredict

Interactor 1: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Interactor 2: COIA1 (P39060)
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]
Gene: COL18A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.670

The method score is based on:

Property Details
Experiments 28514442, 33961781, 12690120
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001501 - skeletal system development
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0062023 - collagen-containing extracellular matrix
GO:0070062 - extracellular exosome
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

1 1754
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024