HitPredict

Interactor 1: PO2F1 (P14859)
POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1)
Gene: POU2F1

Interactor 2: PO2F1 (P14859)
POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1)
Gene: POU2F1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 25416956, 32296183, 11583619, unassigned1304, 20211142
Identification Methods two hybrid, x-ray crystallography, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain, Homeodomain~Pou, Pou~Pou
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 743
Hs

1 743
+ Mm
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+ Dm
+ Dm
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+ Dm
+ Mm
+ At
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+ At
+ Hs
+ Dm
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+ Mm

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Last updated: 15 Jul 2024