Interactor 1: GBRA1 (P14867)
Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1) (GABAAR subunit alpha-1)
Gene: GABRA1

Interactor 2: GBRB2 (P47870)
Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) (GABAAR subunit beta-2)
Gene: GABRB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 11278514, 36030824
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0004890 - GABA-A receptor activity
GO:0005886 - plasma membrane
GO:0007214 - gamma-aminobutyric acid signaling pathway
GO:0022851 - GABA-gated chloride ion channel activity
GO:0030659 - cytoplasmic vesicle membrane
and 10 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 456
Hs

1 512
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Rn
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024