Interactor 1: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1

Interactor 2: FOXO1 (Q12778)
Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma)
Gene: FOXO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.55 0.458

The method score is based on:

Property Details
Experiments 36964488
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0031490 - chromatin DNA binding
Homologous interactions 0

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Last updated: 11Aug2025