Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP
Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.925 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8074697, 26496610, 7651399, 20936779, 8749329 |
| Identification Methods | pull down, affinity chromatography technology, two hybrid, far western blotting, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | APC_15aa~Arm, APC_rep~Arm, Arm~Arm |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005912 - adherens junction and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
