HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 894
+	Hs
		542244 PLAK_HUMAN (1-745): 0: 551: 100.00		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Hs
		542243 PLAK_HUMAN (1-745): 0: 551: 100.00		EPHA5_HUMAN (2-812): 0: 622: 20.39
+	Hs
		542333 PLAK_HUMAN (1-745): 0: 551: 100.00		EPHA7_HUMAN (2-837): 0: 621: 19.50
+	Hs
		542198 PLAK_HUMAN (1-745): 0: 551: 100.00		EPHB2_HUMAN (2-837): 0: 605: 19.58
+	Hs
		716907 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA5_HUMAN (2-812): 0: 622: 20.39
+	Hs
		717105 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA7_HUMAN (2-837): 0: 621: 19.50
+	Hs
		665553 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHB2_HUMAN (2-837): 0: 605: 19.58
+	Hs
		665156 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		665443 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA8_HUMAN (2-824): 0: 590: 19.20
+	Mm
		546270 PLAK_MOUSE (1-745): 0: 553: 98.39		INSR_MOUSE (232-851): 2.75e-135: 439: 26.37
+	Dm
		578636 ARM_DROME (2-730): 6.94e-161: 488: 60.33		Q0KIF4_DROME (2-825): 6.43e-155: 484: 19.00
+	Rn
		544931 CTNB1_RAT (1-731): 1.13e-173: 519: 67.38		INSR_RAT (276-851): 1.26e-134: 437: 27.83
+	Hs
		441449 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		542212 PLAK_HUMAN (1-745): 0: 551: 100.00		RYK_HUMAN (521-810): 4.45e-57: 209: 37.63
+	Hs
		713763 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RYK_HUMAN (521-810): 4.45e-57: 209: 37.63
+	Hs
		507826 PLAK_HUMAN (1-745): 0: 551: 100.00		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435524 PLAK_HUMAN (1-745): 0: 551: 100.00		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		717022 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42
+	Hs
		507882 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435557 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07