HitPredict - High confidence protein-protein interactions

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.954

Property	Details
Experiments	27684187, 26496610, 9535896, 11712088, 34079125, 36652389, 17510365
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Arm~Arm
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 15 others more... GO:0005911 - cell-cell junction GO:0005912 - adherens junction GO:0005925 - focal adhesion GO:0016342 - catenin complex GO:0019903 - protein phosphatase binding GO:0030018 - Z disc GO:0032993 - protein-DNA complex GO:0045294 - alpha-catenin binding GO:0045296 - cadherin binding GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060070 - canonical Wnt signaling pathway GO:0070062 - extracellular exosome GO:0071681 - cellular response to indole-3-methanol GO:0098609 - cell-cell adhesion GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1	745
Hs

1	781

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024