HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12370829
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 1337
+	Hs
		717036 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRJ_HUMAN (1-1337): 0: 925: 100.00
+	Hs
		576992 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRA_HUMAN (521-1304): 2.08e-110: 368: 19.78
+	Hs
		489895 PLAK_HUMAN (1-745): 0: 551: 100.00		PTPRF_HUMAN (189-971): 2.78e-83: 303: 14.68
+	Rn
		1145481 CTNB1_RAT (1-731): 1.13e-173: 519: 67.38		PTPRF_RAT (191-971): 2.27e-85: 310: 14.99
+	Mm
		56908 CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38		PTPRF_MOUSE (191-976): 1.62e-85: 310: 15.02
+	Hs
		489914 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRF_HUMAN (189-971): 2.78e-83: 303: 14.68
+	Mm
		472765 PLAK_MOUSE (1-745): 0: 553: 98.39		PTPRQ_MOUSE (74-1096): 7.76e-72: 268: 12.33
+	Mm
		472764 CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38		PTPRQ_MOUSE (74-1096): 7.76e-72: 268: 12.33
+	Hs
		617080 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRG_HUMAN (757-1329): 3.11e-55: 213: 17.43
+	Hs
		617157 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRZ_HUMAN (760-1324): 8.39e-54: 209: 18.59
+	Hs
		573593 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTN1_HUMAN (1033-1290): 1.72e-55: 201: 36.84
+	Dm
		90970 ARM_DROME (2-730): 6.94e-161: 488: 60.33		E1JJE4_DROME (149-1088): 4.93e-58: 222: 11.68
+	Hs
		542330 PLAK_HUMAN (1-745): 0: 551: 100.00		PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10
+	Hs
		717099 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10
+	Hs
		616904 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRB_HUMAN (463-930): 1.38e-23: 111: 16.63
+	Hs
		717127 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRO_HUMAN (46-453): 1.96e-21: 103: 14.92
+	Mm
		660881 CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38		PTPRM_MOUSE (114-507): 2.59e-17: 90.5: 11.66
+	Hs
		717247 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRU_HUMAN (184-488): 1.18e-15: 85.1: 11.75
+	Hs
		441183 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTPRC_HUMAN (47-298): 3.49e-10: 67: 9.89
+	Dm
		561758 ARM_DROME (2-730): 6.94e-161: 488: 60.33		PTP69_DROME (27-440): 2.09e-19: 97.4: 11.98