HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: NFAC4 (Q14934)
Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T-cell transcription factor NFAT3) (NF-AT3)
Gene: NFATC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 902
+	Hs
		587447 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		NFKB1_HUMAN (375-834): 2.17e-100: 337: 16.73
+	Hs
		717015 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		TF65_HUMAN (404-900): 3.85e-58: 210: 16.41
+	Mm
		970122 CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38		TF65_MOUSE (404-900): 4.17e-56: 205: 17.59
+	Hs
		542170 PLAK_HUMAN (1-745): 0: 551: 100.00		MUC1_HUMAN (2-465): 3.92e-25: 114: 12.37
+	Hs
		554276 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		MUC1_HUMAN (2-465): 3.92e-25: 114: 12.37
+	Hs
		716905 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		SC24C_HUMAN (18-292): 9.59e-09: 61.4: 13.82
+	Hs
		131378 IMA4_HUMAN (228-670): 5.34e-64: 224: 15.79		NFKB1_HUMAN (375-834): 2.17e-100: 337: 16.73
+	Hs
		587478 IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32		NFKB1_HUMAN (375-834): 2.17e-100: 337: 16.73
+	Hs
		853571 IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06		RELB_HUMAN (288-871): 5.39e-64: 228: 16.75
+	Hs
		134880 IMA3_HUMAN (228-670): 2.7e-65: 227: 16.01		TF65_HUMAN (404-900): 3.85e-58: 210: 16.41
+	Hs
		131419 IMA4_HUMAN (228-670): 5.34e-64: 224: 15.79		TF65_HUMAN (404-900): 3.85e-58: 210: 16.41
+	Hs
		853573 IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06		TF65_HUMAN (404-900): 3.85e-58: 210: 16.41
+	Hs
		239044 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		MUC1_HUMAN (2-465): 3.92e-25: 114: 12.37
+	Hs
		853242 IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32		RELB_HUMAN (288-871): 5.39e-64: 228: 16.75
+	Hs
		238659 IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86		RELB_HUMAN (288-871): 5.39e-64: 228: 16.75
+	Hs
		853247 IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32		TF65_HUMAN (404-900): 3.85e-58: 210: 16.41
+	Hs
		238660 IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86		TF65_HUMAN (404-900): 3.85e-58: 210: 16.41
+	Hs
		317987 ARMC8_HUMAN (135-530): 3.88e-16: 84.5: 19.12		NFAC1_HUMAN (18-889): 4.02e-69: 249: 32.15