HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: GMCL1 (Q96IK5)
Germ cell-less protein-like 1 (Spermatogenesis-associated protein 29)
Gene: GMCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 515
+	Hs
		853683 IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		853314 IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32		Q53SE7_HUMAN (1-515): 0: 543: 100.00
+	Hs
		853425 IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Dm
		283973 O76521_DROME (229-679): 6.52e-67: 232: 15.42		KELC_DROME (59-351): 2.5e-76: 263: 17.51
+	Hs
		238706 IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86		KLHL7_HUMAN (86-417): 4.84e-82: 268: 14.67
+	Hs
		168654 IMA6_HUMAN (273-659): 3.11e-41: 160: 13.95		KLHL7_HUMAN (86-417): 4.84e-82: 268: 14.67
+	Hs
		238676 IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86		KEAP1_HUMAN (31-360): 4.2e-73: 245: 15.00
+	Hs
		853453 IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32		BTBD2_HUMAN (86-366): 4.52e-67: 226: 19.08