HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~HMG_box
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 2517
+	Hs
		134956 IMA3_HUMAN (228-670): 2.7e-65: 227: 16.01		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		716868 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		818698 CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38		SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44
+	Hs
		542170 PLAK_HUMAN (1-745): 0: 551: 100.00		MUC1_HUMAN (290-979): 5.97e-38: 159: 15.12
+	Hs
		542475 PLAK_HUMAN (1-745): 0: 551: 100.00		LEF1_HUMAN (929-1200): 1.93e-32: 134: 21.82
+	Hs
		554276 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		MUC1_HUMAN (290-979): 5.97e-38: 159: 15.12
+	Dm
		578629 ARM_DROME (2-730): 6.94e-161: 488: 60.33		PANG1_DROME (911-1183): 2.87e-46: 182: 21.74
+	Hs
		716823 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Mm
		776233 CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38		SOX6_MOUSE (887-1313): 8.49e-33: 141: 15.33
+	Hs
		717411 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		LEF1_HUMAN (929-1200): 1.93e-32: 134: 21.82
+	Dr
		1225024 Q8JID2_DANRE (1-742): 1.57e-166: 500: 66.62		Q9W7C0_DANRE (929-1207): 1.03e-37: 148: 21.51
+	Hs
		133758 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		SOX1_HUMAN (1103-1182): 1.59e-26: 116: 36.25
+	Hs
		542282 PLAK_HUMAN (1-745): 0: 551: 100.00		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78
+	Hs
		717440 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		717002 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78
+	Hs
		239076 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		239044 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		MUC1_HUMAN (290-979): 5.97e-38: 159: 15.12
+	Hs
		134850 IMA3_HUMAN (228-670): 2.7e-65: 227: 16.01		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Ce
		1014329 BAR1_CAEEL (120-658): 1.54e-85: 289: 24.27		POP1_CAEEL (959-1182): 1.17e-34: 141: 22.17
+	Hs
		134987 IMA3_HUMAN (228-670): 2.7e-65: 227: 16.01		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06