HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: PKP2 (Q99959)
Plakophilin-2
Gene: PKP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.713

The method score is based on:

Property Details
Experiments 11790773
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Arm
Common GO terms GO:0001533 - cornified envelope
GO:0002159 - desmosome assembly
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005882 - intermediate filament
and 13 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 745
Hs

1 881
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024