HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: CAD10 (Q9Y6N8)
Cadherin-10 (T2-cadherin)
Gene: CDH10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	24722188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Arm~CADH_Y-type_LIR
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0016342 - catenin complex GO:0045296 - cadherin binding GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 788
+	Hs
		716914 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CADH6_HUMAN (1-788): 0: 836: 72.69
+	Hs
		542247 PLAK_HUMAN (1-745): 0: 551: 100.00		CADH8_HUMAN (1-788): 0: 781: 57.70
+	Hs
		716915 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CADH8_HUMAN (1-788): 0: 781: 57.70
+	Hs
		542286 PLAK_HUMAN (1-745): 0: 551: 100.00		DSC2_HUMAN (33-777): 0: 623: 27.49
+	Hs
		542185 PLAK_HUMAN (1-745): 0: 551: 100.00		CADH3_HUMAN (29-785): 0: 621: 32.09
+	Hs
		542323 PLAK_HUMAN (1-745): 0: 551: 100.00		DSC3_HUMAN (33-777): 0: 619: 28.48
+	Hs
		521702 PLAK_HUMAN (1-745): 0: 551: 100.00		CADH1_HUMAN (2-785): 0: 615: 32.25
+	Hs
		606301 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CADH3_HUMAN (29-785): 0: 621: 32.09
+	Hs
		521758 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CADH1_HUMAN (2-785): 0: 615: 32.25
+	Cl
		80821 CTNB1_CANLF (1-731): 1.59e-173: 519: 67.38		CADH1_CANLF (32-785): 0: 607: 34.07
+	Hs
		542294 PLAK_HUMAN (1-745): 0: 551: 100.00		DSC1_HUMAN (27-776): 0: 569: 28.36
+	Mm
		877530 PLAK_MOUSE (1-745): 0: 553: 98.39		CADH5_MOUSE (2-513): 2.78e-89: 299: 23.12
+	Hs
		542209 PLAK_HUMAN (1-745): 0: 551: 100.00		CADH5_HUMAN (2-513): 3.87e-88: 296: 23.21
+	Hs
		702745 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CADH5_HUMAN (2-513): 3.87e-88: 296: 23.21
+	Hs
		542491 PLAK_HUMAN (1-745): 0: 551: 100.00		X5DQT8_HUMAN (665-788): 1.77e-80: 259: 100.00
+	Hs
		542178 PLAK_HUMAN (1-745): 0: 551: 100.00		CADH2_HUMAN (1-479): 1.25e-66: 239: 20.95
+	Hs
		716913 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CADH4_HUMAN (1-485): 6.14e-72: 255: 19.81
+	Gg
		193807 O42486_CHICK (1-731): 4.63e-176: 525: 67.51		CADH2_CHICK (1-483): 1.03e-66: 240: 20.00
+	Hs
		580207 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CADH2_HUMAN (1-479): 1.25e-66: 239: 20.95
+	Hs
		716916 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		CAD11_HUMAN (11-381): 1.11e-60: 221: 18.53