Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A

Interactor 2: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.55 0.585

The method score is based on:

Property Details
Experiments 20467437, 11101529
Identification Methods affinity chromatography technology, biochemical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 1 others

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Homologous interactions 0

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Last updated: 11Aug2025