Interactor 1: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF

Interactor 2: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.964

The method score is based on:

Property Details
Experiments 28205554, 31980649, 17979178, 19727074, 25437913, 22169110, 22510884, 25155755
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, cosedimentation in solution, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~PK_Tyr_Ser-Thr, C1_1~RBD, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, RBD~RBD
Common GO terms GO:0000165 - MAPK cascade
GO:0002318 - myeloid progenitor cell differentiation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity
and 57 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 766
Hs

1 766
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024