HitPredict

Interactor 1: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF

Interactor 2: RAP1A (P62834)
Ras-related protein Rap-1A (EC 3.6.5.2) (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1)
Gene: RAP1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 16507992, 10454553, 26280580
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Ras, RBD~Ras
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016079 - synaptic vesicle exocytosis
GO:0043005 - neuron projection
GO:0044877 - protein-containing complex binding
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 766
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024