HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: EF3A (P16521)
Elongation factor 3A (EF-3) (EF-3A) (EC 3.6.4.-) (Eukaryotic elongation factor 3) (eEF3) (Translation elongation factor 3A) (Yeast elongation factor 3)
Gene: YEF3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	16554755, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 1044
+	Sc
		544218 HSC82_YEAST (1-705): 0: 977: 100.00		EF3B_YEAST (1-1044): 0: 635: 83.81
+	Sc
		365733 HSP82_YEAST (1-705): 0: 968: 95.63		EF3A_YEAST (1-1044): 0: 640: 100.00
+	Ca
		639865 HSP90_CANAL (4-705): 0: 953: 82.36		EF3_CANAL (2-1044): 0: 594: 76.53
+	Sc
		544552 HSC82_YEAST (1-705): 0: 977: 100.00		NEW1_YEAST (11-1039): 9.7e-141: 454: 33.40
+	Sc
		367040 HSP82_YEAST (1-705): 0: 968: 95.63		NEW1_YEAST (11-1039): 9.7e-141: 454: 33.40
+	Sc
		543486 HSC82_YEAST (1-705): 0: 977: 100.00		GCN1_YEAST (5-465): 9.92e-73: 267: 19.83
+	Sc
		366065 HSP82_YEAST (1-705): 0: 968: 95.63		GCN1_YEAST (5-465): 9.92e-73: 267: 19.83
+	Sc
		543810 HSC82_YEAST (1-705): 0: 977: 100.00		ARB1_YEAST (766-1041): 7.09e-31: 131: 14.95
+	Sc
		366351 HSP82_YEAST (1-705): 0: 968: 95.63		ARB1_YEAST (766-1041): 7.09e-31: 131: 14.95
+	Sc
		543939 HSC82_YEAST (1-705): 0: 977: 100.00		GCN20_YEAST (631-1027): 1.84e-27: 121: 19.21
+	Sc
		366472 HSP82_YEAST (1-705): 0: 968: 95.63		GCN20_YEAST (631-1027): 1.84e-27: 121: 19.21
+	Dm
		1182035 Q9VAY2_DROME (3-676): 0: 833: 47.09		Q7KTD0_DROME (761-988): 1.06e-18: 94.2: 14.59