HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: RCC1 (P21827)
Guanine nucleotide exchange factor SRM1 (Pheromone response pathway component SRM1) (Pre-mRNA-processing protein 20) (Regulator of chromosome condensation) (Suppressor of receptor mutations 1) (mRNA transport protein 1)
Gene: SRM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 482
+	Hs
		438360 HS90B_HUMAN (5-705): 0: 1022: 61.15		RCBT1_HUMAN (71-419): 3.08e-59: 205: 20.62
+	Hs
		432067 HS90A_HUMAN (4-705): 0: 1013: 60.67		RCBT1_HUMAN (71-419): 3.08e-59: 205: 20.62
+	Hs
		438245 HS90B_HUMAN (5-705): 0: 1022: 61.15		HERC4_HUMAN (3-178): 7.5e-25: 110: 12.99
+	Hs
		431935 HS90A_HUMAN (4-705): 0: 1013: 60.67		HERC4_HUMAN (3-178): 7.5e-25: 110: 12.99
+	Hs
		438333 HS90B_HUMAN (5-705): 0: 1022: 61.15		HERC6_HUMAN (3-111): 6.35e-16: 82.9: 14.55
+	Hs
		307240 HS90B_HUMAN (5-705): 0: 1022: 61.15		RCBT2_HUMAN (346-473): 5.87e-16: 82.1: 17.83
+	Hs
		438382 HS90B_HUMAN (5-705): 0: 1022: 61.15		NEK9_HUMAN (19-173): 3.69e-15: 80.2: 10.97
+	Hs
		432034 HS90A_HUMAN (4-705): 0: 1013: 60.67		HERC6_HUMAN (3-111): 6.35e-16: 82.9: 14.55
+	Hs
		307238 HS90A_HUMAN (4-705): 0: 1013: 60.67		RCBT2_HUMAN (346-473): 5.87e-16: 82.1: 17.83
+	Hs
		432092 HS90A_HUMAN (4-705): 0: 1013: 60.67		NEK9_HUMAN (19-173): 3.69e-15: 80.2: 10.97
+	Hs
		438311 HS90B_HUMAN (5-705): 0: 1022: 61.15		NEK8_HUMAN (3-98): 1.04e-10: 65.9: 12.50
+	Hs
		432008 HS90A_HUMAN (4-705): 0: 1013: 60.67		NEK8_HUMAN (3-98): 1.04e-10: 65.9: 12.50
+	Hs
		319705 ENPL_HUMAN (3-680): 0: 893: 47.10		HERC2_HUMAN (339-479): 3.41e-09: 61.7: 15.60