HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: EFGM (P25039)
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)
Gene: MEF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19536198, 15766533
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 761
+	Sc
		365839 HSP82_YEAST (1-705): 0: 968: 95.63		EFGM_YEAST (1-761): 0: 760: 100.00
+	Hs
		437850 HS90B_HUMAN (5-705): 0: 1022: 61.15		EF2_HUMAN (54-761): 0: 627: 20.40
+	Hs
		431483 HS90A_HUMAN (4-705): 0: 1013: 60.67		EF2_HUMAN (54-761): 0: 627: 20.40
+	Hs
		438180 HS90B_HUMAN (5-705): 0: 1022: 61.15		U5S1_HUMAN (15-760): 0: 596: 17.29
+	Hs
		431861 HS90A_HUMAN (4-705): 0: 1013: 60.67		U5S1_HUMAN (15-760): 0: 596: 17.29
+	Sc
		543368 HSC82_YEAST (1-705): 0: 977: 100.00		EF2_YEAST (55-761): 0: 608: 19.86
+	Sc
		365955 HSP82_YEAST (1-705): 0: 968: 95.63		EF2_YEAST (55-761): 0: 608: 19.86
+	Ca
		804505 HSP90_CANAL (4-705): 0: 953: 82.36		EF2_CANAL (55-761): 0: 600: 20.34
+	Hs
		538238 ENPL_HUMAN (3-680): 0: 893: 47.10		U5S1_HUMAN (15-760): 0: 596: 17.29