HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: HS104 (P31539)
Heat shock protein 104 (Protein aggregation-remodeling factor HSP104)
Gene: HSP104

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	31399574, 37295430, 36704946, 37968396, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity GO:0051082 - unfolded protein binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 908
+	Sc
		365946 HSP82_YEAST (1-705): 0: 968: 95.63		HS104_YEAST (1-908): 0: 893: 100.00
+	Sc
		543476 HSC82_YEAST (1-705): 0: 977: 100.00		HSP78_YEAST (103-867): 0: 747: 42.53
+	Sc
		366056 HSP82_YEAST (1-705): 0: 968: 95.63		HSP78_YEAST (103-867): 0: 747: 42.53
+	Hs
		431599 HS90A_HUMAN (4-705): 0: 1013: 60.67		LONM_HUMAN (326-881): 1.99e-80: 282: 13.84