HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: EF2 (P32324)
Elongation factor 2 (EF-2) (EC 3.6.5.-) (Eukaryotic elongation factor 2) (eEF2) (Ribosomal translocase) (Translation elongation factor 2)
Gene: EFT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31399574, 37295430, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 842
+	Hs
		437850 HS90B_HUMAN (5-705): 0: 1022: 61.15		EF2_HUMAN (1-842): 0: 970: 65.97
+	Hs
		431483 HS90A_HUMAN (4-705): 0: 1013: 60.67		EF2_HUMAN (1-842): 0: 970: 65.97
+	Sc
		365955 HSP82_YEAST (1-705): 0: 968: 95.63		EF2_YEAST (1-842): 0: 957: 100.00
+	Ca
		804505 HSP90_CANAL (4-705): 0: 953: 82.36		EF2_CANAL (1-842): 0: 949: 88.01
+	Hs
		438180 HS90B_HUMAN (5-705): 0: 1022: 61.15		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Hs
		431861 HS90A_HUMAN (4-705): 0: 1013: 60.67		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Hs
		538238 ENPL_HUMAN (3-680): 0: 893: 47.10		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Sc
		366111 HSP82_YEAST (1-705): 0: 968: 95.63		SN114_YEAST (2-839): 0: 580: 25.06
+	Sc
		543246 HSC82_YEAST (1-705): 0: 977: 100.00		EFGM_YEAST (6-829): 0: 562: 19.43
+	Sc
		365839 HSP82_YEAST (1-705): 0: 968: 95.63		EFGM_YEAST (6-829): 0: 562: 19.43