HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: NDI1 (P32340)
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial (EC 1.6.5.9) (Internal NADH dehydrogenase) (NADH:ubiquinone reductase (non-electrogenic))
Gene: NDI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	37295430, 22940862, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 513
+	Sc
		365960 HSP82_YEAST (1-705): 0: 968: 95.63		NDI1_YEAST (1-513): 8.71e-139: 411: 100.00
+	Sc
		543838 HSC82_YEAST (1-705): 0: 977: 100.00		NDH1_YEAST (10-508): 6.17e-114: 349: 43.56
+	Sc
		366378 HSP82_YEAST (1-705): 0: 968: 95.63		NDH1_YEAST (10-508): 6.17e-114: 349: 43.56
+	Sc
		365616 HSP82_YEAST (1-705): 0: 968: 95.63		DLDH_YEAST (51-492): 1.28e-73: 243: 12.22
+	Ca
		804485 HSP90_CANAL (4-705): 0: 953: 82.36		Q59RQ6_CANAL (37-492): 5.8e-66: 223: 14.26
+	Hs
		452606 ENPL_HUMAN (3-680): 0: 893: 47.10		DLDH_HUMAN (50-490): 3.18e-87: 279: 14.89