HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: MYO4 (P32492)
Myosin-4 (SWI5-dependent HO expression protein 1)
Gene: MYO4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.634

Property	Details
Experiments	11805826, 19536198, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 1471
+	Sc
		365986 HSP82_YEAST (1-705): 0: 968: 95.63		MYO4_YEAST (1-1471): 0: 1226: 100.00
+	Sc
		543165 HSC82_YEAST (1-705): 0: 977: 100.00		MYO2_YEAST (1-1428): 0: 1103: 48.58
+	Sc
		365763 HSP82_YEAST (1-705): 0: 968: 95.63		MYO2_YEAST (1-1428): 0: 1103: 48.58
+	Ca
		804553 HSP90_CANAL (4-705): 0: 953: 82.36		Q5AKW2_CANAL (3-1442): 0: 1091: 43.05
+	Hs
		438608 HS90B_HUMAN (5-705): 0: 1022: 61.15		MYO15_HUMAN (48-892): 0: 943: 33.22
+	Hs
		538410 ENPL_HUMAN (3-680): 0: 893: 47.10		MYO10_HUMAN (3-1001): 0: 930: 31.07
+	Hs
		431480 HS90A_HUMAN (4-705): 0: 1013: 60.67		MYH7_HUMAN (692-1134): 1.62e-15: 84.7: 7.02
+	Hs
		437945 HS90B_HUMAN (5-705): 0: 1022: 61.15		MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18
+	Hs
		431590 HS90A_HUMAN (4-705): 0: 1013: 60.67		MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18