HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: EI2BB (P32502)
Translation initiation factor eIF2B subunit beta (GCD complex subunit GCD7) (Guanine nucleotide exchange factor subunit GCD7) (eIF2B GDP-GTP exchange factor subunit beta)
Gene: GCD7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 19536198
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 381
+	Sc
		365989 HSP82_YEAST (1-705): 0: 968: 95.63		EI2BB_YEAST (1-381): 3.87e-131: 382: 100.00
+	Sc
		539938 HSC82_YEAST (1-705): 0: 977: 100.00		EI2BA_YEAST (73-370): 4.84e-77: 242: 23.08
+	Sc
		365701 HSP82_YEAST (1-705): 0: 968: 95.63		EI2BA_YEAST (73-370): 4.84e-77: 242: 23.08
+	Sc
		544461 HSC82_YEAST (1-705): 0: 977: 100.00		MTNA_YEAST (11-357): 1.23e-68: 223: 15.67
+	Sc
		366937 HSP82_YEAST (1-705): 0: 968: 95.63		MTNA_YEAST (11-357): 1.23e-68: 223: 15.67
+	Ca
		804536 HSP90_CANAL (4-705): 0: 953: 82.36		Q5ADR6_CANAL (83-368): 1.88e-62: 210: 16.35
+	Pf
		1211643 Q8IC05_PLAF7 (1-705): 0: 959: 57.79		Q8I4S8_PLAF7 (148-376): 7.75e-58: 201: 28.26