HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: IMB2 (P38217)
Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN)
Gene: KAP104

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31399574, 37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 918
+	Sc
		366184 HSP82_YEAST (1-705): 0: 968: 95.63		IMB2_YEAST (1-918): 0: 580: 100.00
+	Mm
		432420 HS90A_MOUSE (4-705): 0: 1012: 60.59		IMB1_MOUSE (13-885): 3.2e-96: 324: 11.87
+	Sc
		543372 HSC82_YEAST (1-705): 0: 977: 100.00		IMB3_YEAST (9-858): 2.92e-90: 311: 15.32
+	Sc
		365959 HSP82_YEAST (1-705): 0: 968: 95.63		IMB3_YEAST (9-858): 2.92e-90: 311: 15.32
+	Sc
		544439 HSC82_YEAST (1-705): 0: 977: 100.00		IMB1_YEAST (14-865): 3.48e-86: 296: 12.25
+	Sc
		366915 HSP82_YEAST (1-705): 0: 968: 95.63		IMB1_YEAST (14-865): 3.48e-86: 296: 12.25
+	Ca
		804489 HSP90_CANAL (4-705): 0: 953: 82.36		Q59VX7_CANAL (13-848): 4.21e-85: 293: 12.80