HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: NMD5 (P46970)
Nonsense-mediated mRNA decay protein 5 (Karyopherin-119)
Gene: NMD5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 37295430
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 1048
+	Sc
		366511 HSP82_YEAST (1-705): 0: 968: 95.63		NMD5_YEAST (1-1048): 0: 640: 100.00
+	Mm
		432420 HS90A_MOUSE (4-705): 0: 1012: 60.59		IMB1_MOUSE (5-930): 2.5e-119: 389: 11.01
+	Sc
		544361 HSC82_YEAST (1-705): 0: 977: 100.00		SXM1_YEAST (4-1047): 1.31e-120: 394: 24.29
+	Sc
		366841 HSP82_YEAST (1-705): 0: 968: 95.63		SXM1_YEAST (4-1047): 1.31e-120: 394: 24.29
+	Dm
		1361623 Q9VAY2_DROME (3-676): 0: 833: 47.09		IPO9_DROME (4-1042): 2.42e-113: 377: 12.41
+	Sc
		544099 HSC82_YEAST (1-705): 0: 977: 100.00		IMB5_YEAST (1-1046): 1.7e-25: 116: 13.38
+	Sc
		544439 HSC82_YEAST (1-705): 0: 977: 100.00		IMB1_YEAST (1-820): 5.56e-19: 95.1: 11.06
+	Sc
		366915 HSP82_YEAST (1-705): 0: 968: 95.63		IMB1_YEAST (1-820): 5.56e-19: 95.1: 11.06
+	Ca
		804489 HSP90_CANAL (4-705): 0: 953: 82.36		Q59VX7_CANAL (6-869): 6.8e-20: 97.7: 13.25